A Cynomolgus macaque is a standard primate species that is mainly distributed in East Asia and south of Southeast Asia. This is one of the most commonly used non-human primates in biomedical research because its genome is extremely human and easy to conduct in experiments.
Introduction to Sinomolgus macaque
Cynomolgus macaque (Macaca fascicularis) Cynomolgus macaque (Macaca fascicularis), also known as long-legged macaque and crab-eating macaque, is a species native to tropical southern and southeast Asia.
Their activities include virgin forests, secondary forests, mangroves, and other adjacent forests that are sometimes found in rural and suburban areas.
They have different types of food sources. In addition to crabs, fruits, leaves, small animals and birds are the things they serve.
Cynomolgus macaque can, for example, feed and acquire social behaviors that indicate its behavioral homology to humans.
It is also because of other common characteristics with humans, that it is used in bio-biological studies as an important organism model, such as drug evaluation.
Despite their increasing importance as animal models, the genome of the Cynomolgus macaque has not been fully characterized, precluding the molecular studies of this model.
Application of the Cynomolgus macaque in biomedical research
Behavioral science has attracted considerable attention as a platform for studying human cognitive function. However, due to ethical considerations, some advanced functional and structural investigations cannot be conducted in humans.
Cynomolgus macaques share powerful genetic, neuroanatomical, and behavioral homology to humans.
Therefore, this species serves as a more appropriate experimental model for neuropsychiatric studies and other behavioral studies compared to non-primate behavioral models (e.g., rodents, canines).
Also, Psychomolgus macaque has been recognized as a suitable model for transplantation research because they have similarities with humans in the immunological, genetic, and physiologic aspects.
Furthermore, they are also used to study the toxicity and efficacy of drug development, to develop vaccine candidates for selected animal models, particularly those associated with emerging dangerous pathogens.
For example, because of their high level of MHC class allele sharing, cynomolgus macaques may serve as the best alternative for rhesus monkeys to study HIV / AIDS.
And the hepatitis B virus naturally occurs and gets infected with the Cynomolgus macaques, making the Cynomolgus macaques a good nonhuman primate animal for research on the Hepatitis B virus.
In addition to being used as an animal model, the biological products of Cynomolgus macaque also play a very important role in the in vitro study. Peripheral blood mononuclear cells (PBMCs) were used to detect the FC-dependent function of antibodies isolated from monomegalous monkeys.
The primary blocking step involves applying cyanomegalus serum to various immunoassays, such as ELISA, ELISPOT, and Western blots.
The serum or plasma of these animals can also be used to study in vitro PK profiles of novel therapeutics.
For many years, Creative BioLabs has focused on delivering quality primary products to customers worldwide and accelerating their projects.
We supply the pharmaceutical, biotechnology, diagnostics and analytical lab industries to Sinemolgus macaque-derived serum, plasma, primary cells, body fluids, and tissue samples.
We provide a variety of customized research products and related services to suit your specific needs. If you have any other questions about this, please feel free to contact us.
Other Recommended Reading
- Dent’s Mona Monkey Facts | Profile | Habitat
- Finger Marmoset Facts – Pet | Cost | Monkey
- Adult Marmoset – Pygmy Marmoset Description
- Baby Pygmy Marmoset – Monkey | Size | For Adoption
- Marmoset Pet Monkey – Care | Price | For Sale
- Pygmy Marmoset Pet – Care | Price | For Sale
- Golden Marmoset – Monkey | Size | Baby | Lion
- 30 Interesting Facts about Jane Goodall
- How Many Types of Macaques Are There?
- Is it Good to Have a Macaque as A Pet?
- How Much is the Chimpanzee Strength?
- Interesting Facts about Chimpanzees Habitat
- Amazing Chimpanzee Adaptations for Survival
- 6 Very Interesting Baby Chimpanzee Facts
- Macaque Monkey Baby Life Cycle and Facts
- Bush Baby Animal Description and Facts
- Is a Bush Baby Pet Legal or Ethical?
- Lesser Bushbaby Description | Profile | Facts
- Cute Bush Baby or Galago Profile and Facts
- African bush baby Profile and Description
